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Insulin-like Growth Factor-1 and IGF Binding Proteins Predict All-Cause Mortality and Morbidity in Older Adults
While the growth hormone/insulin-like growth factor-1 (GH/IGF-1) pathway plays essential roles in growth and development, diminished signaling via this pathway in model organisms extends lifespan and health-span. In humans, circulating IGF-1 and IGF-binding proteins 3 and 1 (IGFBP-3 and 1), surrogat...
Autores principales: | Zhang, William B., Aleksic, Sandra, Gao, Tina, Weiss, Erica F., Demetriou, Eleni, Verghese, Joe, Holtzer, Roee, Barzilai, Nir, Milman, Sofiya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349399/ https://www.ncbi.nlm.nih.gov/pubmed/32492897 http://dx.doi.org/10.3390/cells9061368 |
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