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The Function of Mitochondrial Calcium Uniporter at the Whole-Cell and Single Mitochondrion Levels in WT, MICU1 KO, and MICU2 KO Cells
Mitochondrial Ca(2+) ([Ca(2+)](M)) uptake through its Ca(2+) uniporter (MCU) is central to many cell functions such as bioenergetics, spatiotemporal organization of Ca(2+) signals, and apoptosis. MCU activity is regulated by several intrinsic proteins including MICU1, MICU2, and EMRE. While signific...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349584/ https://www.ncbi.nlm.nih.gov/pubmed/32580385 http://dx.doi.org/10.3390/cells9061520 |