Cargando…

PPARG Pro12Ala Polymorphism with CKD in Asians: A Meta-Analysis Combined with a Case-Control Study—A Key for Reaching Null Association

Background: So far, numerous meta-analyses have been published regarding the correlation between peroxisome proliferator-activated receptor gamma (PPARG) proline 12 alanine (Pro12Ala) gene polymorphism and chronic kidney disease (CKD); however, the results appear to be contradictory. Hence, this stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Hsiang-Cheng, Chen, Wei-Teing, Sung, Tzu-Ling, Tsai, Dung-Jang, Lin, Chin, Su, Hao, Lin, Yuh-Feng, Chiu, Hung-Yi, Su, Sui-Lung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349649/ https://www.ncbi.nlm.nih.gov/pubmed/32604723 http://dx.doi.org/10.3390/genes11060705

Ejemplares similares

The Effect of PPARγ rs1801282 Variant on Mortality Risk Among Asians With Chronic Kidney Disease: A Cohort Study and Meta-Analysis
por: Chen, Wei-Teing, et al.
Publicado: (2022)

Prevalence of the Pro12Ala missense mutation in the PPARG2 gene in Kuwaiti patients with primary knee osteoarthritis
por: Al-Jarallah, Khaled F., et al.
Publicado: (2011)

PPARG (Pro12Ala) genetic variant and risk of T2DM: a systematic review and meta-analysis
por: Sarhangi, Negar, et al.
Publicado: (2020)

Diet and PPARG2 Pro12Ala Polymorphism Interactions in Relation to Cancer Risk: A Systematic Review
por: Tran, Lieu, et al.
Publicado: (2021)

Decisive evidence corroborates a null relationship between MTHFR C677T and chronic kidney disease: A case–control study and a meta-analysis
por: Chang, Hsueh-Lu, et al.
Publicado: (2020)

Pro12Ala Polymorphism in the PPARG Gene Contributes to the Development of Diabetic Nephropathy in Chinese Type 2 Diabetic Patients
por: Liu, Limei, et al.
Publicado: (2010)

Genotype-based recall to study metabolic effects of genetic variation: a pilot study of PPARG Pro12Ala carriers
por: Kamble, Prasad G., et al.
Publicado: (2017)

Correlation between PPARG Pro12Ala Polymorphism and Therapeutic Responses to Thiazolidinediones in Patients with Type 2 Diabetes: A Meta-Analysis
por: Jang, Eun Jeong, et al.
Publicado: (2023)

The Decisive Case-Control Study Elaborates the Null Association between ADAMTS5 rs226794 and Osteoarthritis in Asians: A Case-Control Study and Meta-Analysis
por: Kao, Chung-Cheng, et al.
Publicado: (2021)

Sex Dimorphism of Nonalcoholic Fatty Liver Disease (NAFLD) in Pparg-Null Mice
por: Schiffrin, Mariano, et al.
Publicado: (2021)

Effect of the PPARG2 Pro12Ala Polymorphism and Clinical Risk Factors for Diabetes Mellitus on HbA1c in the Japanese General Population
Publicado: (2012)

The Single Nucleotide Polymorphism PPARG2 Pro12Ala Affects Body Mass Index, Fat Mass, and Blood Pressure in Severely Obese Patients
por: Rodrigues, Ana Paula dos Santos, et al.
Publicado: (2018)

The Decisive Case-Control Study Elaborates the Null Association between ESR1 XbaI and Osteoarthritis in Asians: A Case–Control Study and Meta-Analysis
por: Huang, Yu-Hao, et al.
Publicado: (2021)

Nephropathy in Pparg-null mice highlights PPARγ systemic activities in metabolism and in the immune system
por: Toffoli, Barbara, et al.
Publicado: (2017)

A predictive model for progression of CKD
por: Chang, Hsueh-Lu, et al.
Publicado: (2019)

Effect of the PPARG2 Pro12Ala Polymorphism on Associations of Physical Activity and Sedentary Time with Markers of Insulin Sensitivity in Those with an Elevated Risk of Type 2 Diabetes
por: Yates, Thomas, et al.
Publicado: (2015)

PPARG2 Pro12Ala polymorphism influences body composition changes in severely obese patients consuming extra virgin olive oil: a randomized clinical trial
por: Rodrigues, Ana Paula Santos, et al.
Publicado: (2018)

Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk
por: Sanghera, Dharambir K, et al.
Publicado: (2008)

Angiotensin II receptor type 1 A1166C modifies the association between angiotensinogen M235T and chronic kidney disease
por: Su, Sui-Lung, et al.
Publicado: (2017)

PPARG2 Pro12Ala and TNFα -308G>A Polymorphisms Are Not Associated with Heart Failure Development in Patients with Ischemic Heart Disease after Coronary Artery Bypass Grafting
por: Wojtkowska, Izabela, et al.
Publicado: (2019)

The Genetics of PPARG and the Skeleton
por: Ackert-Bicknell, Cheryl, et al.
Publicado: (2006)

The Association Between the Peroxisome Proliferator-Activated Receptor-γ2 (PPARG2) Pro12Ala Gene Variant and Type 2 Diabetes Mellitus: A HuGE Review and Meta-Analysis
por: Gouda, Hebe N., et al.
Publicado: (2010)

Breast-Feeding Modulates the Influence of the Peroxisome Proliferator–Activated Receptor-γ (PPARG2) Pro12Ala Polymorphism on Adiposity in Adolescents: The Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) cross-sectional study
por: Verier, Caroline, et al.
Publicado: (2010)

A Simple Algorithm Using Ventilator Parameters to Predict Successfully Rapid Weaning Program in Cardiac Intensive Care Unit Patients
por: Chen, Wei-Teing, et al.
Publicado: (2022)

CKD-MBD KDIGO guidelines: how difficult is reaching the ‘target’?
por: Cozzolino, Mario
Publicado: (2018)

PPARG: A Novel Target for Yellow Tea in Kidney Stone Prevention
por: Su, Mingjie, et al.
Publicado: (2023)

Modification of Diet in Renal Disease (MDRD) Study and CKD Epidemiology Collaboration (CKD-EPI) Equations for Taiwanese Adults
por: Chen, Ling-I, et al.
Publicado: (2014)

Association of PPARγ2 (Pro12Ala) and Neuropeptide Y (Leu7Pro) Gene Polymorphisms with Obstructive Sleep Apnea in Obese Asian Indians
por: Bhushan, Bharat, et al.
Publicado: (2011)

PPARG as therapeutic target for antifibrotic therapy
por: Ghallab, Ahmed, et al.
Publicado: (2020)

Pparg signaling controls bladder cancer subtype and immune exclusion
por: Tate, Tiffany, et al.
Publicado: (2021)

PARP1 rs1136410 Val762Ala contributes to an increased risk of overall cancer in the East Asian population: a meta-analysis
por: Xin, Yijuan, et al.
Publicado: (2021)

The Polymorphism at PLCB4 Promoter (rs6086746) Changes the Binding Affinity of RUNX2 and Affects Osteoporosis Susceptibility: An Analysis of Bioinformatics-Based Case-Control Study and Functional Validation
por: Tsai, Dung-Jang, et al.
Publicado: (2021)

Association between Pro12Ala polymorphism and albuminuria in type 2 diabetic nephropathy
por: Chen, Yung‐Nien, et al.
Publicado: (2020)

Pparg may Promote Chemosensitivity of Hypopharyngeal Squamous Cell Carcinoma
por: Lian, Meng, et al.
Publicado: (2020)

PPARG Binding Landscapes in Macrophages Suggest a Genome-Wide Contribution of PU.1 to Divergent PPARG Binding in Human and Mouse
por: Pott, Sebastian, et al.
Publicado: (2012)

Evaluation of single nucleotide polymorphisms of Pro12Ala in peroxisome proliferator-activated receptor-γ and Gly308Ala in tumor necrosis factor-α genes in obese Asian Indians: a population-based study
por: Bhagat, Namita, et al.
Publicado: (2010)

Homozygosity for the Ala Allele of the PPARγ2 Pro12Ala Polymorphism Is Associated with Reduced Risk of Coronary Artery Disease
por: Galgani, Andrea, et al.
Publicado: (2010)

Gain of C-Ala enables AlaRS to target the L-shaped tRNA(Ala)
por: Antika, Titi Rindi, et al.
Publicado: (2022)

Regulation of chemokine and chemokine receptor expression by PPARG in adipocytes and macrophages
por: Nguyen, MT Audrey, et al.
Publicado: (2011)

PPARγ2(Pro12Ala) Polymorphism and Human Health
por: He, Weimin
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_g1u1fov1odmopuj1cv902e3eoc