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Inhibition of ABCC6 Transporter Modifies Cytoskeleton and Reduces Motility of HepG2 Cells via Purinergic Pathway

ABCC6, belonging to sub-family C of ATP-binding cassette transporter, is an ATP-dependent transporter mainly present in the basolateral plasma membrane of hepatic and kidney cells. Although the substrates transported are still uncertain, ABCC6 has been shown to promote ATP release. The extracellular...

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Detalles Bibliográficos
Autores principales: Ostuni, Angela, Carmosino, Monica, Miglionico, Rocchina, Abruzzese, Vittorio, Martinelli, Fabio, Russo, Daniela, Laurenzana, Ilaria, Petillo, Agata, Bisaccia, Faustino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349786/
https://www.ncbi.nlm.nih.gov/pubmed/32517079
http://dx.doi.org/10.3390/cells9061410