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Cisplatin Protein Binding Partners and Their Relevance for Platinum Drug Sensitivity

Cisplatin is a widely used drug in the treatment of various solid tumors, such as ovarian cancer. However, while the acquired resistance significantly limits the success of therapy, some tumors, such as colorectal cancer, are intrinsically insensitive to cisplatin. Only a small amount of intracellul...

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Detalles Bibliográficos
Autores principales: Möltgen, Sophie, Piumatti, Eleonora, Massafra, Giuseppe M., Metzger, Sabine, Jaehde, Ulrich, Kalayda, Ganna V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349790/
https://www.ncbi.nlm.nih.gov/pubmed/32466394
http://dx.doi.org/10.3390/cells9061322