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Histone Methyltransferase DOT1L Is Involved in Larval Molting and Second Stage Nymphal Feeding in Ornithodoros moubata

Epigenetic mechanisms have not been characterized in ticks despite their importance as vectors of human and animal diseases worldwide. Our investigation identifies and functionally characterizes the orthologue of S-adenosylmethionine (SAM) binding methyltransferase enzyme, disruptor of telomeric sil...

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Detalles Bibliográficos
Autores principales: Gobl, Julia, Kumar Sinha, Deepak, Sima, Radek, Perner, Jan, Kopáček, Petr, Valdés, James J, Rego, Ryan O. M., Cabezas-Cruz, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349889/
https://www.ncbi.nlm.nih.gov/pubmed/32244625
http://dx.doi.org/10.3390/vaccines8020157