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Alpha glucosidase inhibition activity of phenolic fraction from Simarouba glauca: An in-vitro, in-silico and kinetic study

A phenolic rich fraction purified from Simarouba glauca leaves was effective in alpha glucosidase inhibition. The purified fraction named ‘fraction-14’ had shown significant inhibition of yeast alpha glucosidase enzyme activity (IC(50) = 2.4 ± 0.4 μg/mL) when compared to anti-diabetic drug acarbose...

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Detalles Bibliográficos
Autores principales: Mugaranja, Kirana P., Kulal, Ananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350133/
https://www.ncbi.nlm.nih.gov/pubmed/32671273
http://dx.doi.org/10.1016/j.heliyon.2020.e04392