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Antigen-Specific IFN-γ/IL-17-Co-Producing CD4(+) T-Cells are the Determinants for Protective Efficacy of Tuberculosis Subunit Vaccine
The antigen-specific Th17 responses in the lungs for improved immunity against Mycobacterium tuberculosis (Mtb) infection are incompletely understood. Tuberculosis (TB) vaccine candidate HSP90-ESAT-6 (E6), given as a Bacillus Calmette-Guérin (BCG)-prime boost regimen, confers superior long-term prot...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350228/ https://www.ncbi.nlm.nih.gov/pubmed/32545304 http://dx.doi.org/10.3390/vaccines8020300 |