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Antigen-Specific IFN-γ/IL-17-Co-Producing CD4(+) T-Cells are the Determinants for Protective Efficacy of Tuberculosis Subunit Vaccine

The antigen-specific Th17 responses in the lungs for improved immunity against Mycobacterium tuberculosis (Mtb) infection are incompletely understood. Tuberculosis (TB) vaccine candidate HSP90-ESAT-6 (E6), given as a Bacillus Calmette-Guérin (BCG)-prime boost regimen, confers superior long-term prot...

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Detalles Bibliográficos
Autores principales:	Choi, Han-Gyu, Kwon, Kee Woong, Choi, Seunga, Back, Yong Woo, Park, Hye-Soo, Kang, Soon Myung, Choi, Eunsol, Shin, Sung Jae, Kim, Hwa-Jung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350228/ https://www.ncbi.nlm.nih.gov/pubmed/32545304 http://dx.doi.org/10.3390/vaccines8020300

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