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Immunogenicity and Efficacy of Zika Virus Envelope Domain III in DNA, Protein, and ChAdOx1 Adenoviral-Vectored Vaccines

The flavivirus envelope protein domain III (EDIII) was an effective immunogen against dengue virus (DENV) and other related flaviviruses. Whether this can be applied to the Zika virus (ZIKV) vaccinology remains an open question. Here, we tested the efficacy of ZIKV-EDIII against ZIKV infection, usin...

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Detalles Bibliográficos
Autores principales: López-Camacho, César, De Lorenzo, Giuditta, Slon-Campos, Jose Luis, Dowall, Stuart, Abbink, Peter, Larocca, Rafael A., Kim, Young Chan, Poggianella, Monica, Graham, Victoria, Findlay-Wilson, Stephen, Rayner, Emma, Carmichael, Jennifer, Dejnirattisai, Wanwisa, Boyd, Michael, Hewson, Roger, Mongkolsapaya, Juthathip, Screaton, Gavin R., Barouch, Dan H., Burrone, Oscar R., Patel, Arvind H., Reyes-Sandoval, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350260/
https://www.ncbi.nlm.nih.gov/pubmed/32560145
http://dx.doi.org/10.3390/vaccines8020307