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Adaptive Immunity to Dengue Virus: Slippery Slope or Solid Ground for Rational Vaccine Design?

The four serotypes of dengue virus are the most widespread causes of arboviral disease, currently placing half of the human population at risk of infection. Pre-existing immunity to one dengue virus serotype can predispose to severe disease following secondary infection with a different serotype. Th...

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Detalles Bibliográficos
Autores principales: Wilken, Lucas, Rimmelzwaan, Guus F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350362/
https://www.ncbi.nlm.nih.gov/pubmed/32549226
http://dx.doi.org/10.3390/pathogens9060470