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Two susceptible HLA-DRB1 alleles for multiple sclerosis differentially regulate anti-JC virus antibody serostatus along with fingolimod

BACKGROUND: Progressive multifocal leukoencephalopathy (PML) caused by JC virus (JCV) is a rare but serious complication of some disease-modifying drugs used to treat multiple sclerosis (MS). Japanese MS patients treated with fingolimod were reported to be 10 times more likely to develop PML than eq...

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Detalles Bibliográficos
Autores principales:	Watanabe, Mitsuru, Nakamura, Yuri, Isobe, Noriko, Tanaka, Masami, Sakoda, Ayako, Hayashi, Fumie, Kawano, Yuji, Yamasaki, Ryo, Matsushita, Takuya, Kira, Jun-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350631/ https://www.ncbi.nlm.nih.gov/pubmed/32646493 http://dx.doi.org/10.1186/s12974-020-01865-7

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