Genome-wide studies reveal the essential and opposite roles of ARID1A in controlling human cardiogenesis and neurogenesis from pluripotent stem cells

BACKGROUND: Early human heart and brain development simultaneously occur during embryogenesis. Notably, in human newborns, congenital heart defects strongly associate with neurodevelopmental abnormalities, suggesting a common gene or complex underlying both cardiogenesis and neurogenesis. However, d...

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Detalles Bibliográficos
Autores principales: Liu, Juli, Liu, Sheng, Gao, Hongyu, Han, Lei, Chu, Xiaona, Sheng, Yi, Shou, Weinian, Wang, Yue, Liu, Yunlong, Wan, Jun, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350744/
https://www.ncbi.nlm.nih.gov/pubmed/32646524
http://dx.doi.org/10.1186/s13059-020-02082-4

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