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Anticandidal activities of lactic acid bacteria isolated from the vagina

BACKGROUND/AIM: Lactic acid bacteria prevent the overgrowth of pathogenic agents and opportunistic pathogens in the vagina. Moreover, lactic acid bacteria contribute to the preservation of vaginal microbiota by producing antimicrobial agents. Previous studies showed that some lactic acid bacteria ex...

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Detalles Bibliográficos
Autores principales: ER, Sevda, İSTANBULLU TOSUN, Ayşe, ARIK, Gizem, KIVANÇ, Merih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350877/
https://www.ncbi.nlm.nih.gov/pubmed/30761844
http://dx.doi.org/10.3906/sag-1709-143
Descripción
Sumario:BACKGROUND/AIM: Lactic acid bacteria prevent the overgrowth of pathogenic agents and opportunistic pathogens in the vagina. Moreover, lactic acid bacteria contribute to the preservation of vaginal microbiota by producing antimicrobial agents. Previous studies showed that some lactic acid bacteria exhibited antimicrobial activity against Candida species causing yeast vaginosis as well as many bacterial pathogens. MATERIALS AND METHODS: The antifungal activities of various lactic acid bacteria isolated from the vagina of healthy women on some Candida species isolated from the vagina were investigated by agar diffusion technique. RESULTS: Most of the lactic acid bacteria that belong to the species of Lactobacillus crispatus, L. fermentum, L. acidophilus, L. paracesei subsp. paracesei, L. pentosus, and L. plantarum exhibited antifungal activity in varying ratios against C. albicans, C. glabrata, and C. tropicalis strains isolated from the vagina. CONCLUSION: The lactic acid bacteria are useful microorganisms associated with a variety of probiotic properties. In this sense, our lactic acid bacteria isolates with high antifungal activity may be promising candidates as probiotic microorganisms in the inhibition of vaginal candidiasis, which is one of the most prevalent problems, or in the protection against candidiasis. We will continue our studies in this area.