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Immune Thrombocytopenic Purpura in Patients with COVID-19
We described three COVID-19-infected patients with profound immune thrombocytopenia causing haemorrhagic mucocutaneous complications. We conclude that an immune mechanism was responsible as common causes were excluded. Since corticoids were considered harmful in the circumstances, the patients were...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SMC Media Srl
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350967/ https://www.ncbi.nlm.nih.gov/pubmed/32665935 http://dx.doi.org/10.12890/2020_001751 |
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author | Revuz, Sabine Vernier, Nathalie Saadi, Leilah Campagne, Julien Poussing, Sophie Maurier, François |
author_facet | Revuz, Sabine Vernier, Nathalie Saadi, Leilah Campagne, Julien Poussing, Sophie Maurier, François |
author_sort | Revuz, Sabine |
collection | PubMed |
description | We described three COVID-19-infected patients with profound immune thrombocytopenia causing haemorrhagic mucocutaneous complications. We conclude that an immune mechanism was responsible as common causes were excluded. Since corticoids were considered harmful in the circumstances, the patients were successfully treated with intravenous immunoglobulins without later relapse. LEARNING POINTS: The severity of haemorrhagic syndrome is not correlated with the severity of COVID-19 infection. Thrombocytopenia in mild COVID-19 infection seems to have an autoimmune mechanism. Intravenous immunoglobulins (1 g/kg) should be the first line of treatment. |
format | Online Article Text |
id | pubmed-7350967 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SMC Media Srl |
record_format | MEDLINE/PubMed |
spelling | pubmed-73509672020-07-13 Immune Thrombocytopenic Purpura in Patients with COVID-19 Revuz, Sabine Vernier, Nathalie Saadi, Leilah Campagne, Julien Poussing, Sophie Maurier, François Eur J Case Rep Intern Med Articles We described three COVID-19-infected patients with profound immune thrombocytopenia causing haemorrhagic mucocutaneous complications. We conclude that an immune mechanism was responsible as common causes were excluded. Since corticoids were considered harmful in the circumstances, the patients were successfully treated with intravenous immunoglobulins without later relapse. LEARNING POINTS: The severity of haemorrhagic syndrome is not correlated with the severity of COVID-19 infection. Thrombocytopenia in mild COVID-19 infection seems to have an autoimmune mechanism. Intravenous immunoglobulins (1 g/kg) should be the first line of treatment. SMC Media Srl 2020-06-09 /pmc/articles/PMC7350967/ /pubmed/32665935 http://dx.doi.org/10.12890/2020_001751 Text en © EFIM 2020 This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Articles Revuz, Sabine Vernier, Nathalie Saadi, Leilah Campagne, Julien Poussing, Sophie Maurier, François Immune Thrombocytopenic Purpura in Patients with COVID-19 |
title | Immune Thrombocytopenic Purpura in Patients with COVID-19 |
title_full | Immune Thrombocytopenic Purpura in Patients with COVID-19 |
title_fullStr | Immune Thrombocytopenic Purpura in Patients with COVID-19 |
title_full_unstemmed | Immune Thrombocytopenic Purpura in Patients with COVID-19 |
title_short | Immune Thrombocytopenic Purpura in Patients with COVID-19 |
title_sort | immune thrombocytopenic purpura in patients with covid-19 |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350967/ https://www.ncbi.nlm.nih.gov/pubmed/32665935 http://dx.doi.org/10.12890/2020_001751 |
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