Brief validation of the novel GeneXpert Xpress SARS-CoV-2 PCR assay

The clinical and epidemiologic management of the SARS-CoV-2 pandemic is critically dependent on molecular assays with short turn-around time. We validated the novel Xpert Xpress SARS-CoV-2 assay using a commercial nucleic acid testing (Roche Cobas 6800). We found an excellent concordance over a rang...

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Autores principales: Goldenberger, Daniel, Leuzinger, Karoline, Sogaard, Kirstine K., Gosert, Rainer, Roloff, Tim, Naegele, Klaudia, Cuénod, Aline, Mari, Alfredo, Seth-Smith, Helena, Rentsch, Katharina, Hinić, Vladimira, Hirsch, Hans H., Egli, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351036/
https://www.ncbi.nlm.nih.gov/pubmed/32659240
http://dx.doi.org/10.1016/j.jviromet.2020.113925
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author Goldenberger, Daniel
Leuzinger, Karoline
Sogaard, Kirstine K.
Gosert, Rainer
Roloff, Tim
Naegele, Klaudia
Cuénod, Aline
Mari, Alfredo
Seth-Smith, Helena
Rentsch, Katharina
Hinić, Vladimira
Hirsch, Hans H.
Egli, Adrian
author_facet Goldenberger, Daniel
Leuzinger, Karoline
Sogaard, Kirstine K.
Gosert, Rainer
Roloff, Tim
Naegele, Klaudia
Cuénod, Aline
Mari, Alfredo
Seth-Smith, Helena
Rentsch, Katharina
Hinić, Vladimira
Hirsch, Hans H.
Egli, Adrian
author_sort Goldenberger, Daniel
collection PubMed
description The clinical and epidemiologic management of the SARS-CoV-2 pandemic is critically dependent on molecular assays with short turn-around time. We validated the novel Xpert Xpress SARS-CoV-2 assay using a commercial nucleic acid testing (Roche Cobas 6800). We found an excellent concordance over a range of SARS-CoV-2 loads and across established human coronaviruses.
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spelling pubmed-73510362020-07-13 Brief validation of the novel GeneXpert Xpress SARS-CoV-2 PCR assay Goldenberger, Daniel Leuzinger, Karoline Sogaard, Kirstine K. Gosert, Rainer Roloff, Tim Naegele, Klaudia Cuénod, Aline Mari, Alfredo Seth-Smith, Helena Rentsch, Katharina Hinić, Vladimira Hirsch, Hans H. Egli, Adrian J Virol Methods Article The clinical and epidemiologic management of the SARS-CoV-2 pandemic is critically dependent on molecular assays with short turn-around time. We validated the novel Xpert Xpress SARS-CoV-2 assay using a commercial nucleic acid testing (Roche Cobas 6800). We found an excellent concordance over a range of SARS-CoV-2 loads and across established human coronaviruses. Elsevier B.V. 2020-10 2020-07-10 /pmc/articles/PMC7351036/ /pubmed/32659240 http://dx.doi.org/10.1016/j.jviromet.2020.113925 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Goldenberger, Daniel
Leuzinger, Karoline
Sogaard, Kirstine K.
Gosert, Rainer
Roloff, Tim
Naegele, Klaudia
Cuénod, Aline
Mari, Alfredo
Seth-Smith, Helena
Rentsch, Katharina
Hinić, Vladimira
Hirsch, Hans H.
Egli, Adrian
Brief validation of the novel GeneXpert Xpress SARS-CoV-2 PCR assay
title Brief validation of the novel GeneXpert Xpress SARS-CoV-2 PCR assay
title_full Brief validation of the novel GeneXpert Xpress SARS-CoV-2 PCR assay
title_fullStr Brief validation of the novel GeneXpert Xpress SARS-CoV-2 PCR assay
title_full_unstemmed Brief validation of the novel GeneXpert Xpress SARS-CoV-2 PCR assay
title_short Brief validation of the novel GeneXpert Xpress SARS-CoV-2 PCR assay
title_sort brief validation of the novel genexpert xpress sars-cov-2 pcr assay
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351036/
https://www.ncbi.nlm.nih.gov/pubmed/32659240
http://dx.doi.org/10.1016/j.jviromet.2020.113925
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