The importance of cycle threshold values in interpreting molecular tests for SARS-CoV-2

Using the Allplex™ 2019-nCoV assay (Seegene, South Korea), 285 samples were tested; 49 (17%) were positive for 3 genes, 4 (1.4%) samples were positive for 2 genes (all N gene and RdRP gene), 8 (3%) samples were positive for 1 gene (all N gene only), and 224 (78.5%) samples were negative.

Detalles Bibliográficos
Autores principales: Drew, Richard J., O'Donnell, Sinéad, LeBlanc, David, McMahon, Mary, Natin, Dominic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Virology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351062/
https://www.ncbi.nlm.nih.gov/pubmed/32711184
http://dx.doi.org/10.1016/j.diagmicrobio.2020.115130
_version_ 1783557383164788736
author Drew, Richard J.
O'Donnell, Sinéad
LeBlanc, David
McMahon, Mary
Natin, Dominic
author_facet Drew, Richard J.
O'Donnell, Sinéad
LeBlanc, David
McMahon, Mary
Natin, Dominic
author_sort Drew, Richard J.
collection PubMed
description Using the Allplex™ 2019-nCoV assay (Seegene, South Korea), 285 samples were tested; 49 (17%) were positive for 3 genes, 4 (1.4%) samples were positive for 2 genes (all N gene and RdRP gene), 8 (3%) samples were positive for 1 gene (all N gene only), and 224 (78.5%) samples were negative.
format Online
Article
Text
id pubmed-7351062
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier Inc.
record_format MEDLINE/PubMed
spelling pubmed-73510622020-07-13 The importance of cycle threshold values in interpreting molecular tests for SARS-CoV-2 Drew, Richard J. O'Donnell, Sinéad LeBlanc, David McMahon, Mary Natin, Dominic Diagn Microbiol Infect Dis Virology Using the Allplex™ 2019-nCoV assay (Seegene, South Korea), 285 samples were tested; 49 (17%) were positive for 3 genes, 4 (1.4%) samples were positive for 2 genes (all N gene and RdRP gene), 8 (3%) samples were positive for 1 gene (all N gene only), and 224 (78.5%) samples were negative. Elsevier Inc. 2020-11 2020-07-10 /pmc/articles/PMC7351062/ /pubmed/32711184 http://dx.doi.org/10.1016/j.diagmicrobio.2020.115130 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Virology
Drew, Richard J.
O'Donnell, Sinéad
LeBlanc, David
McMahon, Mary
Natin, Dominic
The importance of cycle threshold values in interpreting molecular tests for SARS-CoV-2
title The importance of cycle threshold values in interpreting molecular tests for SARS-CoV-2
title_full The importance of cycle threshold values in interpreting molecular tests for SARS-CoV-2
title_fullStr The importance of cycle threshold values in interpreting molecular tests for SARS-CoV-2
title_full_unstemmed The importance of cycle threshold values in interpreting molecular tests for SARS-CoV-2
title_short The importance of cycle threshold values in interpreting molecular tests for SARS-CoV-2
title_sort importance of cycle threshold values in interpreting molecular tests for sars-cov-2
topic Virology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351062/
https://www.ncbi.nlm.nih.gov/pubmed/32711184
http://dx.doi.org/10.1016/j.diagmicrobio.2020.115130
work_keys_str_mv AT drewrichardj theimportanceofcyclethresholdvaluesininterpretingmoleculartestsforsarscov2
AT odonnellsinead theimportanceofcyclethresholdvaluesininterpretingmoleculartestsforsarscov2
AT leblancdavid theimportanceofcyclethresholdvaluesininterpretingmoleculartestsforsarscov2
AT mcmahonmary theimportanceofcyclethresholdvaluesininterpretingmoleculartestsforsarscov2
AT natindominic theimportanceofcyclethresholdvaluesininterpretingmoleculartestsforsarscov2
AT drewrichardj importanceofcyclethresholdvaluesininterpretingmoleculartestsforsarscov2
AT odonnellsinead importanceofcyclethresholdvaluesininterpretingmoleculartestsforsarscov2
AT leblancdavid importanceofcyclethresholdvaluesininterpretingmoleculartestsforsarscov2
AT mcmahonmary importanceofcyclethresholdvaluesininterpretingmoleculartestsforsarscov2
AT natindominic importanceofcyclethresholdvaluesininterpretingmoleculartestsforsarscov2

Ejemplares similares