Characterization of post-edited cells modified in the TFAM gene by CRISPR/Cas9 technology in the bovine model

Gene editing in large animal models for future applications in translational medicine and food production must be deeply investigated for an increase of knowledge. The mitochondrial transcription factor A (TFAM) is a member of the HMGB subfamily that binds to mtDNA promoters. This gene maintains mtD...

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Detalles Bibliográficos
Autores principales: de Oliveira, Vanessa Cristina, Gomes Mariano Junior, Clésio, Belizário, José Ernesto, Krieger, José Eduardo, Fernandes Bressan, Fabiana, Roballo, Kelly Cristine Santos, Fantinato-Neto, Paulo, Meirelles, Flávio Vieira, Chiaratti, Marcos Roberto, Concordet, Jean-Paul, Ambrósio, Carlos Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351154/
https://www.ncbi.nlm.nih.gov/pubmed/32649732
http://dx.doi.org/10.1371/journal.pone.0235856

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