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JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damage
Ribosomal DNA (rDNA) is the most transcribed genomic region and contains hundreds of tandem repeats. Maintaining these rDNA repeats as well as the level of rDNA transcription is essential for cellular homeostasis. DNA damages generated in rDNA need to be efficiently and accurately repaired and rDNA...
Autores principales: | Fages, Jérémie, Chailleux, Catherine, Humbert, Jonathan, Jang, Suk-Min, Loehr, Jérémy, Lambert, Jean-Philippe, Côté, Jacques, Trouche, Didier, Canitrot, Yvan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351224/ https://www.ncbi.nlm.nih.gov/pubmed/32598339 http://dx.doi.org/10.1371/journal.pgen.1008511 |
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