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Synthesis of a novel PEGylated colon-specific azo-based 4- aminosalicylic acid prodrug
OBJECTIVE(S): 4-aminosalicylic acid (4-ASA) is an isomer of mesalazine that has recently been shown to be effective against inflammatory bowel disease (IBD), and more specifically, ulcerative colitis. However, the majority of orally administered 4-ASA is readily and extensively absorbed from the sto...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Mashhad University of Medical Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351447/ https://www.ncbi.nlm.nih.gov/pubmed/32695295 http://dx.doi.org/10.22038/ijbms.2020.41152.9736 |