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Evolutionarily distant I domains can functionally replace the essential ligand-binding domain of Plasmodium TRAP

Inserted (I) domains function as ligand-binding domains in adhesins that support cell adhesion and migration in many eukaryotic phyla. These adhesins include integrin αβ heterodimers in metazoans and single subunit transmembrane proteins in apicomplexans such as TRAP in Plasmodium and MIC2 in Toxopl...

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Detalles Bibliográficos
Autores principales:	Klug, Dennis, Goellner, Sarah, Kehrer, Jessica, Sattler, Julia, Strauss, Léanne, Singer, Mirko, Lu, Chafen, Springer, Timothy A, Frischknecht, Friedrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Microbiology and Infectious Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351488/ https://www.ncbi.nlm.nih.gov/pubmed/32648541 http://dx.doi.org/10.7554/eLife.57572

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