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A trans-eQTL network regulates osteoclast multinucleation and bone mass
Functional characterisation of cell-type-specific regulatory networks is key to establish a causal link between genetic variation and phenotype. The osteoclast offers a unique model for interrogating the contribution of co-regulated genes to in vivo phenotype as its multinucleation and resorption ac...
Autores principales: | Pereira, Marie, Ko, Jeong-Hun, Logan, John, Protheroe, Hayley, Kim, Kee-Beom, Tan, Amelia Li Min, Croucher, Peter I, Park, Kwon-Sik, Rotival, Maxime, Petretto, Enrico, Bassett, JH Duncan, Williams, Graham R, Behmoaras, Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351491/ https://www.ncbi.nlm.nih.gov/pubmed/32553114 http://dx.doi.org/10.7554/eLife.55549 |
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