Cargando…
Energetics and IC50 based epitope screening in SARS CoV-2 (COVID 19) spike protein by immunoinformatic analysis implicating for a suitable vaccine development
BACKGROUND: The recent outbreak by SARS-CoV-2 has generated a chaos in global health and economy and claimed/infected a large number of lives. Closely resembling with SARS CoV, the present strain has manifested exceptionally higher degree of spreadability, virulence and stability possibly due to som...
Autores principales: | Banerjee, Amrita, Santra, Dipannita, Maiti, Smarajit |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351549/ https://www.ncbi.nlm.nih.gov/pubmed/32650788 http://dx.doi.org/10.1186/s12967-020-02435-4 |
Ejemplares similares
-
Immunoinformatic paradigm predicts macrophage and T-cells epitope responses against globally conserved spike fragments of SARS CoV-2 for universal vaccination
por: Maiti, Smarajit, et al.
Publicado: (2022) -
Global conserved RBD fraction of SARS-CoV-2 S-protein with T500S mutation in silico significantly blocks ACE2 and rejects viral spike
por: Banerjee, Amrita, et al.
Publicado: (2022) -
Molecular dynamic simulation suggests stronger interaction of Omicron-spike with ACE2 than wild but weaker than Delta SARS-CoV-2 can be blocked by engineered S1-RBD fraction
por: Santra, Dipannita, et al.
Publicado: (2022) -
Relation of ACE2 with co-morbidity factors in SARS-CoV-2 pathogenicity
por: Santra, Dipannita, et al.
Publicado: (2023) -
In silico Nigellidine (N. sativa) bind to viral spike/active-sites of ACE1/2, AT1/2 to prevent COVID-19 induced vaso-tumult/vascular-damage/comorbidity
por: Maiti, Smarajit, et al.
Publicado: (2021)