A smart polymer for sequence-selective binding, pulldown, and release of DNA targets

Selective isolation of DNA is crucial for applications in biology, bionanotechnology, clinical diagnostics and forensics. We herein report a smart methanol-responsive polymer (MeRPy) that can be programmed to bind and separate single- as well as double-stranded DNA targets. Captured targets are quic...

Descripción completa

Detalles Bibliográficos
Autores principales: Krieg, Elisha, Gupta, Krishna, Dahl, Andreas, Lesche, Mathias, Boye, Susanne, Lederer, Albena, Shih, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351716/
https://www.ncbi.nlm.nih.gov/pubmed/32651444
http://dx.doi.org/10.1038/s42003-020-1082-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351716/
https://www.ncbi.nlm.nih.gov/pubmed/32651444
http://dx.doi.org/10.1038/s42003-020-1082-2

Ejemplares similares