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Mechano-modulatory synthetic niches for liver organoid derivation

The recent demonstration that primary cells from the liver can be expanded in vitro as organoids holds enormous promise for regenerative medicine and disease modelling. The use of three-dimensional (3D) cultures based on ill-defined and potentially immunogenic matrices, however, hampers the translat...

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Detalles Bibliográficos
Autores principales: Sorrentino, Giovanni, Rezakhani, Saba, Yildiz, Ece, Nuciforo, Sandro, Heim, Markus H., Lutolf, Matthias P., Schoonjans, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351772/
https://www.ncbi.nlm.nih.gov/pubmed/32651372
http://dx.doi.org/10.1038/s41467-020-17161-0