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Mechano-modulatory synthetic niches for liver organoid derivation
The recent demonstration that primary cells from the liver can be expanded in vitro as organoids holds enormous promise for regenerative medicine and disease modelling. The use of three-dimensional (3D) cultures based on ill-defined and potentially immunogenic matrices, however, hampers the translat...
Autores principales: | Sorrentino, Giovanni, Rezakhani, Saba, Yildiz, Ece, Nuciforo, Sandro, Heim, Markus H., Lutolf, Matthias P., Schoonjans, Kristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351772/ https://www.ncbi.nlm.nih.gov/pubmed/32651372 http://dx.doi.org/10.1038/s41467-020-17161-0 |
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