Within-host microevolution of Streptococcus pneumoniae is rapid and adaptive during natural colonisation

Genomic evolution, transmission and pathogenesis of Streptococcus pneumoniae, an opportunistic human-adapted pathogen, is driven principally by nasopharyngeal carriage. However, little is known about genomic changes during natural colonisation. Here, we use whole-genome sequencing to investigate wit...

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Detalles Bibliográficos
Autores principales: Chaguza, Chrispin, Senghore, Madikay, Bojang, Ebrima, Gladstone, Rebecca A., Lo, Stephanie W., Tientcheu, Peggy-Estelle, Bancroft, Rowan E., Worwui, Archibald, Foster-Nyarko, Ebenezer, Ceesay, Fatima, Okoi, Catherine, McGee, Lesley, Klugman, Keith P., Breiman, Robert F., Barer, Michael R., Adegbola, Richard A., Antonio, Martin, Bentley, Stephen D., Kwambana-Adams, Brenda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351774/
https://www.ncbi.nlm.nih.gov/pubmed/32651390
http://dx.doi.org/10.1038/s41467-020-17327-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351774/
https://www.ncbi.nlm.nih.gov/pubmed/32651390
http://dx.doi.org/10.1038/s41467-020-17327-w

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