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Within-host microevolution of Streptococcus pneumoniae is rapid and adaptive during natural colonisation
Genomic evolution, transmission and pathogenesis of Streptococcus pneumoniae, an opportunistic human-adapted pathogen, is driven principally by nasopharyngeal carriage. However, little is known about genomic changes during natural colonisation. Here, we use whole-genome sequencing to investigate wit...
Autores principales: | Chaguza, Chrispin, Senghore, Madikay, Bojang, Ebrima, Gladstone, Rebecca A., Lo, Stephanie W., Tientcheu, Peggy-Estelle, Bancroft, Rowan E., Worwui, Archibald, Foster-Nyarko, Ebenezer, Ceesay, Fatima, Okoi, Catherine, McGee, Lesley, Klugman, Keith P., Breiman, Robert F., Barer, Michael R., Adegbola, Richard A., Antonio, Martin, Bentley, Stephen D., Kwambana-Adams, Brenda A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351774/ https://www.ncbi.nlm.nih.gov/pubmed/32651390 http://dx.doi.org/10.1038/s41467-020-17327-w |
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