Desensitization of transient receptor potential vanilloid type-1 (TRPV1) channel as promising therapy of irritable bowel syndrome: characterization of the action of palvanil in the mouse gastrointestinal tract

TRPV1 are involved in the control of the gastrointestinal (GI) functions and pain sensation. Their activation induces pain but it is followed by desensitization, which in turn causes analgesia. The studies from the last two decades indicate that TRPV1 are involved in visceral hypersensitivity in the...

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Detalles Bibliográficos
Autores principales: Szymaszkiewicz, Agata, Włodarczyk, Jakub, Wasilewski, Andrzej, Di Marzo, Vincenzo, Storr, Martin, Fichna, Jakub, Zielińska, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351811/
https://www.ncbi.nlm.nih.gov/pubmed/32002574
http://dx.doi.org/10.1007/s00210-020-01829-x

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