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Complete dimensional collapse in the continuum limit of a delayed SEIQR network model with separable distributed infectivity

We take up a recently proposed compartmental SEIQR model with delays, ignore loss of immunity in the context of a fast pandemic, extend the model to a network structured on infectivity and consider the continuum limit of the same with a simple separable interaction model for the infectivities [Formu...

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Autores principales: Vyasarayani, C. P., Chatterjee, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352098/
https://www.ncbi.nlm.nih.gov/pubmed/32836812
http://dx.doi.org/10.1007/s11071-020-05785-2
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author Vyasarayani, C. P.
Chatterjee, Anindya
author_facet Vyasarayani, C. P.
Chatterjee, Anindya
author_sort Vyasarayani, C. P.
collection PubMed
description We take up a recently proposed compartmental SEIQR model with delays, ignore loss of immunity in the context of a fast pandemic, extend the model to a network structured on infectivity and consider the continuum limit of the same with a simple separable interaction model for the infectivities [Formula: see text] . Numerical simulations show that the evolving dynamics of the network is effectively captured by a single scalar function of time, regardless of the distribution of [Formula: see text] in the population. The continuum limit of the network model allows a simple derivation of the simpler model, which is a single scalar delay differential equation (DDE), wherein the variation in [Formula: see text] appears through an integral closely related to the moment generating function of [Formula: see text] . If the first few moments of u exist, the governing DDE can be expanded in a series that shows a direct correspondence with the original compartmental DDE with a single [Formula: see text] . Even otherwise, the new scalar DDE can be solved using either numerical integration over u at each time step, or with the analytical integral if available in some useful form. Our work provides a new academic example of complete dimensional collapse, ties up an underlying continuum model for a pandemic with a simpler-seeming compartmental model and will hopefully lead to new analysis of continuum models for epidemics.
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spelling pubmed-73520982020-07-13 Complete dimensional collapse in the continuum limit of a delayed SEIQR network model with separable distributed infectivity Vyasarayani, C. P. Chatterjee, Anindya Nonlinear Dyn Original Paper We take up a recently proposed compartmental SEIQR model with delays, ignore loss of immunity in the context of a fast pandemic, extend the model to a network structured on infectivity and consider the continuum limit of the same with a simple separable interaction model for the infectivities [Formula: see text] . Numerical simulations show that the evolving dynamics of the network is effectively captured by a single scalar function of time, regardless of the distribution of [Formula: see text] in the population. The continuum limit of the network model allows a simple derivation of the simpler model, which is a single scalar delay differential equation (DDE), wherein the variation in [Formula: see text] appears through an integral closely related to the moment generating function of [Formula: see text] . If the first few moments of u exist, the governing DDE can be expanded in a series that shows a direct correspondence with the original compartmental DDE with a single [Formula: see text] . Even otherwise, the new scalar DDE can be solved using either numerical integration over u at each time step, or with the analytical integral if available in some useful form. Our work provides a new academic example of complete dimensional collapse, ties up an underlying continuum model for a pandemic with a simpler-seeming compartmental model and will hopefully lead to new analysis of continuum models for epidemics. Springer Netherlands 2020-07-11 2020 /pmc/articles/PMC7352098/ /pubmed/32836812 http://dx.doi.org/10.1007/s11071-020-05785-2 Text en © Springer Nature B.V. 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Paper
Vyasarayani, C. P.
Chatterjee, Anindya
Complete dimensional collapse in the continuum limit of a delayed SEIQR network model with separable distributed infectivity
title Complete dimensional collapse in the continuum limit of a delayed SEIQR network model with separable distributed infectivity
title_full Complete dimensional collapse in the continuum limit of a delayed SEIQR network model with separable distributed infectivity
title_fullStr Complete dimensional collapse in the continuum limit of a delayed SEIQR network model with separable distributed infectivity
title_full_unstemmed Complete dimensional collapse in the continuum limit of a delayed SEIQR network model with separable distributed infectivity
title_short Complete dimensional collapse in the continuum limit of a delayed SEIQR network model with separable distributed infectivity
title_sort complete dimensional collapse in the continuum limit of a delayed seiqr network model with separable distributed infectivity
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352098/
https://www.ncbi.nlm.nih.gov/pubmed/32836812
http://dx.doi.org/10.1007/s11071-020-05785-2
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