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Semisynthetic Modification of Tau Protein with Di-Ubiquitin Chains for Aggregation Studies
Ubiquitin, a protein modifier that regulates diverse essential cellular processes, is also a component of the protein inclusions characteristic of many neurodegenerative disorders. In Alzheimer’s disease, the microtubule associated tau protein accumulates within damaged neurons in the form of cross-...
Autores principales: | Munari, Francesca, Barracchia, Carlo Giorgio, Parolini, Francesca, Tira, Roberto, Bubacco, Luigi, Assfalg, Michael, D’Onofrio, Mariapina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352214/ https://www.ncbi.nlm.nih.gov/pubmed/32575755 http://dx.doi.org/10.3390/ijms21124400 |
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