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Liposome Consolidated with Cyclodextrin Provides Prolonged Drug Retention Resulting in Increased Drug Bioavailability in Brain
Although butylidenephthalide (BP) is an efficient anticancer drug, its poor bioavailability renders it ineffective for treating drug-resistant brain tumors. However, this problem is overcome through the use of noninvasive delivery systems, including intranasal administration. Herein, the bioavailabi...
Autores principales: | Lin, En-Yi, Chen, Yu-Shuan, Li, Yuan-Sheng, Chen, Syuan-Rong, Lee, Chia-Hung, Huang, Mao-Hsuan, Chuang, Hong-Meng, Harn, Horng-Jyh, Yang, Hsueh-Hui, Lin, Shinn-Zong, Tai, Dar-Fu, Chiou, Tzyy-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352271/ https://www.ncbi.nlm.nih.gov/pubmed/32575820 http://dx.doi.org/10.3390/ijms21124408 |
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