Cargando…

Inactivation of APC Induces CD34 Upregulation to Promote Epithelial-Mesenchymal Transition and Cancer Stem Cell Traits in Pancreatic Cancer

Pancreatic cancer (PC) is a highly lethal malignancy due to the cancer routinely being diagnosed late and having a limited response to chemotherapy. Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic malignant tumor, representing more than 85% of all pancreatic cancers. In...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hsieh, Mei Jen, Chiu, Tai-Jan, Lin, Yu Chun, Weng, Ching-Chieh, Weng, Yu-Ting, Hsiao, Chang-Chun, Cheng, Kuang-hung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352299/ https://www.ncbi.nlm.nih.gov/pubmed/32586050 http://dx.doi.org/10.3390/ijms21124473

Ejemplares similares

The Use of Genetically Engineered Mouse Models for Studying the Function of Mutated Driver Genes in Pancreatic Cancer
por: Weng, Ching-Chieh, et al.
Publicado: (2019)

Mutant Kras-induced upregulation of CD24 enhances prostate cancer stemness and bone metastasis
por: Weng, Ching-Chieh, et al.
Publicado: (2018)

Loss of the transcriptional repressor TGIF1 results in enhanced Kras-driven development of pancreatic cancer
por: Weng, Ching-Chieh, et al.
Publicado: (2019)

Inhibition of β-Catenin Activity Abolishes LKB1 Loss-Driven Pancreatic Cystadenoma in Mice
por: Hsieh, Mei-Jen, et al.
Publicado: (2021)

Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation
por: Miguchi, Masashi, et al.
Publicado: (2016)

Intestinal Apc‐inactivation induces HSP25 dependency
por: van Neerven, Sanne M, et al.
Publicado: (2022)

SMAD4 Loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells
por: Chen, Yu-Wen, et al.
Publicado: (2014)

Mutational inactivation of Apc in the intestinal epithelia compromises cellular organisation
por: Rannikmae, Helena, et al.
Publicado: (2021)

MEGF11 is related to tumour recurrence in triple negative breast cancer via chemokine upregulation
por: Chiu, Jen-Hwey, et al.
Publicado: (2020)

First-decade patient with colorectal cancer carrying both germline and somatic mutations in APC gene
por: Yeh, Yung-Sung, et al.
Publicado: (2017)

Cancer Stemness in Apc- vs. Apc/KRAS-Driven Intestinal Tumorigenesis
por: Ghazvini, Mehrnaz, et al.
Publicado: (2013)

Ensemble biomarkers for guiding anti‐angiogenesis therapy for ovarian cancer using deep learning
por: Wang, Ching‐Wei, et al.
Publicado: (2023)

Fumarate hydratase inhibits non-small cell lung cancer metastasis via inactivation of AMPK and upregulation of DAB2
por: Vadhan, Anupama, et al.
Publicado: (2022)

Bioactive Vitamin D Attenuates MED28-Mediated Cell Growth and Epithelial–Mesenchymal Transition in Human Colorectal Cancer Cells
por: Huang, Chun-Yin, et al.
Publicado: (2022)

The HDAC Inhibitor LBH589 Induces ERK-Dependent Prometaphase Arrest in Prostate Cancer via HDAC6 Inactivation and Down-Regulation
por: Chuang, Mei-Jen, et al.
Publicado: (2013)

Calcitriol Suppresses Warburg Effect and Cell Growth in Human Colorectal Cancer Cells
por: Huang, Chun-Yin, et al.
Publicado: (2021)

USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development
por: Novellasdemunt, Laura, et al.
Publicado: (2023)

Upregulation of CENP-H in tongue cancer correlates with poor prognosis and progression
por: Liao, Wen-Ting, et al.
Publicado: (2009)

Cephalosporin-Glycopeptide Combinations for Use against Clinical Methicillin-Resistant Staphylococcus aureus Isolates: Enhanced In vitro Antibacterial Activity
por: Tang, Hung-Jen, et al.
Publicado: (2017)

Curcumin Suppresses Metastasis via Sp-1, FAK Inhibition, and E-Cadherin Upregulation in Colorectal Cancer
por: Chen, Chun-Chieh, et al.
Publicado: (2013)

APC Promoter Methylation in Gastrointestinal Cancer
por: Zhu, Lila, et al.
Publicado: (2021)

Making the Invisible Visible: Toward High-Quality Terahertz Tomographic Imaging via Physics-Guided Restoration
por: Su, Weng-Tai, et al.
Publicado: (2023)

NAP1L1: A Novel Human Colorectal Cancer Biomarker Derived From Animal Models of Apc Inactivation
por: Queiroz, Cleberson J. S., et al.
Publicado: (2020)

Reappraisal of VEGF in the Pathogenesis of Kawasaki Disease
por: Chen, Chun-Yu, et al.
Publicado: (2022)

PKM2 is not required for colon cancer initiated by APC loss
por: Lau, Allison N., et al.
Publicado: (2017)

Prevalence of APC and PTEN Alterations in Urachal Cancer
por: Nagy, Nikolett, et al.
Publicado: (2020)

CD9 Upregulation-Decreased CCL21 Secretion in Mesenchymal Stem Cells Reduces Cancer Cell Migration
por: Hsieh, Chia-Chu, et al.
Publicado: (2021)

Enterocyte-Specific Inactivation of SIRT1 Reduces Tumor Load in the APC(+/min) Mouse Model
por: Leko, Vid, et al.
Publicado: (2013)

TORC1 inactivation promotes APC/C-dependent mitotic slippage in yeast and human cells
por: Yamada, Chihiro, et al.
Publicado: (2021)

Association between depressive disorders and risk of breast cancer recurrence after curative surgery
por: Chen, Shaw-Ji, et al.
Publicado: (2016)

Artificial neural network approach to predict surgical site infection after free-flap reconstruction in patients receiving surgery for head and neck cancer
por: Kuo, Pao-Jen, et al.
Publicado: (2018)

Integrated analysis of fine-needle-aspiration cystic fluid proteome, cancer cell secretome, and public transcriptome datasets for papillary thyroid cancer biomarker discovery
por: Wu, Chia-Chun, et al.
Publicado: (2018)

C1-inactivator is upregulated in glioblastoma
por: Förnvik, Karolina, et al.
Publicado: (2017)

The Optimization of Plasma-Activated Water Treatments to Inactivate Salmonella Enteritidis (ATCC 13076) on Shell Eggs
por: Lin, Chia-Min, et al.
Publicado: (2019)

Tumor suppressive functions of hsa-miR-34a on cell cycle, migration and protective autophagy in bladder cancer
por: Hwang, Thomas I-Sheng, et al.
Publicado: (2023)

Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells
por: King, Lauren E., et al.
Publicado: (2016)

RB Maintains Quiescence and Prevents Premature Senescence through Upregulation of DNMT1 in Mesenchymal Stromal Cells
por: Lin, Shih-Pei, et al.
Publicado: (2014)

Pinosylvin inhibits migration and invasion of nasopharyngeal carcinoma cancer cells via regulation of epithelial-mesenchymal transition and inhibition of MMP-2
por: Chuang, Yi-Ching, et al.
Publicado: (2021)

Risk of cancer in patients with genital warts: A nationwide, population-based cohort study in Taiwan
por: Cho, Ching-Yi, et al.
Publicado: (2017)

A Weakly Supervised Deep Learning Method for Guiding Ovarian Cancer Treatment and Identifying an Effective Biomarker
por: Wang, Ching-Wei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_e35sl79nnsb52pfnvjobr0avim