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Pharmacogenomic Analysis Reveals CCNA2 as a Predictive Biomarker of Sensitivity to Polo-Like Kinase I Inhibitor in Gastric Cancer

Despite recent innovations and advances in early diagnosis, the prognosis of advanced gastric cancer remains poor due to a limited number of available therapeutics. Here, we employed pharmacogenomic analysis of 37 gastric cancer cell lines and 1345 small-molecule pharmacological compounds to investi...

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Detalles Bibliográficos
Autores principales: Lee, Yunji, Lee, Chae Eun, Oh, Sejin, Kim, Hakhyun, Lee, Jooyoung, Kim, Sang Bum, Kim, Hyun Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352331/
https://www.ncbi.nlm.nih.gov/pubmed/32486290
http://dx.doi.org/10.3390/cancers12061418