CYP3A5 Genotype as a Potential Pharmacodynamic Biomarker for Tacrolimus Therapy in Ulcerative Colitis in Japanese Patients

Tacrolimus has been used to induce remission in patients with steroid-refractory ulcerative colitis. It poses a problem of large individual differences in dosage necessary to attain target blood concentration and, often, this leads to drug inefficacy. We examined the difference in mRNA expression le...

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Detalles Bibliográficos
Autores principales: Yamamoto, Yuki, Nakase, Hiroshi, Matsuura, Minoru, Maruyama, Shihoko, Masuda, Satohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352351/
https://www.ncbi.nlm.nih.gov/pubmed/32570960
http://dx.doi.org/10.3390/ijms21124347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352351/
https://www.ncbi.nlm.nih.gov/pubmed/32570960
http://dx.doi.org/10.3390/ijms21124347

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