Non-Anticoagulant Heparan Sulfate from the Ascidian Phallusia nigra Prevents Colon Carcinoma Metastasis in Mice by Disrupting Platelet-Tumor Cell Interaction

Although metastasis is the primary cause of death in patients with malignant solid tumors, efficient anti-metastatic therapies are not clinically available currently. Sulfated glycosaminoglycans from marine sources have shown promising pharmacological effects, acting on different steps of the metast...

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Detalles Bibliográficos
Autores principales: Silva, Christiane F. S., Motta, Juliana M., Teixeira, Felipe C. O. B., Gomes, Angélica M., Vilanova, Eduardo, Kozlowski, Eliene O., Borsig, Lubor, Pavão, Mauro S. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352385/
https://www.ncbi.nlm.nih.gov/pubmed/32466418
http://dx.doi.org/10.3390/cancers12061353

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