Specific Roles of HSP27 S15 Phosphorylation Augmenting the Nuclear Function of HER2 to Promote Trastuzumab Resistance

Trastuzumab (TZMB) is widely used as first line therapy for breast cancer (BC) patients overexpressing human epidermal growth factor receptor 2 (HER2). Despite its clinical benefits, many patients suffer from primary or secondary resistance to this drug within one year. As diverse molecular mechanis...

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Detalles Bibliográficos
Autores principales: Hwang, Soo-Yeon, Choi, Seul-Ki, Seo, Seung Hee, Jo, Hyunji, Shin, Jae-Ho, Na, Younghwa, Lee, Yun-Sil, Kwon, Youngjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352409/
https://www.ncbi.nlm.nih.gov/pubmed/32545363
http://dx.doi.org/10.3390/cancers12061540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352409/
https://www.ncbi.nlm.nih.gov/pubmed/32545363
http://dx.doi.org/10.3390/cancers12061540

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