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Advances in Deubiquitinating Enzyme Inhibition and Applications in Cancer Therapeutics

Since the discovery of the ubiquitin proteasome system (UPS), the roles of ubiquitinating and deubiquitinating enzymes (DUBs) have been widely elucidated. The ubiquitination of proteins regulates many aspects of cellular functions such as protein degradation and localization, and also modifies prote...

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Detalles Bibliográficos
Autores principales:	Antao, Ainsley Mike, Tyagi, Apoorvi, Kim, Kye-Seong, Ramakrishna, Suresh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352412/ https://www.ncbi.nlm.nih.gov/pubmed/32549302 http://dx.doi.org/10.3390/cancers12061579

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