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Telomerase Biogenesis and Activities from the Perspective of Its Direct Interacting Partners

Telomerase reverse transcriptase (TERT)—the catalytic subunit of telomerase—is reactivated in up to 90% of all human cancers. TERT is observed in heterogenous populations of protein complexes, which are dynamically regulated in a cell type- and cell cycle-specific manner. Over the past two decades,...

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Detalles Bibliográficos
Autores principales: Nguyen, Kathryn T. T. T., Wong, Judy M. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352425/
https://www.ncbi.nlm.nih.gov/pubmed/32599885
http://dx.doi.org/10.3390/cancers12061679