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Preparation of a Ceramic Matrix Composite Made of Hydroxyapatite Nanoparticles and Polylactic Acid by Consolidation of Composite Granules

Composites made of a biodegradable polymer, e.g., polylactic acid (PLA) and hydroxyapatite nanoparticles (HAP NPs) are promising orthopedic materials. There is a particular need for biodegradable hybrid nanocomposites with strong mechanical properties. However, obtaining such composites is challengi...

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Autores principales: Pietrzykowska, Elzbieta, Romelczyk-Baishya, Barbara, Wojnarowicz, Jacek, Sokolova, Marina, Szlazak, Karol, Swieszkowski, Wojciech, Locs, Janis, Lojkowski, Witold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352493/
https://www.ncbi.nlm.nih.gov/pubmed/32486301
http://dx.doi.org/10.3390/nano10061060
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author Pietrzykowska, Elzbieta
Romelczyk-Baishya, Barbara
Wojnarowicz, Jacek
Sokolova, Marina
Szlazak, Karol
Swieszkowski, Wojciech
Locs, Janis
Lojkowski, Witold
author_facet Pietrzykowska, Elzbieta
Romelczyk-Baishya, Barbara
Wojnarowicz, Jacek
Sokolova, Marina
Szlazak, Karol
Swieszkowski, Wojciech
Locs, Janis
Lojkowski, Witold
author_sort Pietrzykowska, Elzbieta
collection PubMed
description Composites made of a biodegradable polymer, e.g., polylactic acid (PLA) and hydroxyapatite nanoparticles (HAP NPs) are promising orthopedic materials. There is a particular need for biodegradable hybrid nanocomposites with strong mechanical properties. However, obtaining such composites is challenging, since nanoparticles tend to agglomerate, and it is difficult to achieve good bonding between the hydrophilic ceramic and the hydrophobic polymer. This paper describes a two-step technology for obtaining a ceramic matrix composite. The first step is the preparation of composite granules. The granules are obtained by infiltration of porous granules of HAP NPs with PLA through high-pressure infiltration. The homogeneous ceramic-polymer granules are 80 μm in diameter, and the composite granules are 80 wt% HAP NPs. The second step is consolidation of the granules using high pressure. This is performed in three variants: Uniaxial pressing with the pressure of up to 1000 MPa at room temperature, warm isostatic compaction (75 MPa at 155 °C), and a combination of the two methods. The combined methods result in the highest densification (99%) and strongest mechanical properties; the compressive strength is 374 MPa. The structure of the ceramic matrix composite is homogeneous. Good adhesion between the inorganic and the organic component is observable using scanning electron microscopy.
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spelling pubmed-73524932020-07-15 Preparation of a Ceramic Matrix Composite Made of Hydroxyapatite Nanoparticles and Polylactic Acid by Consolidation of Composite Granules Pietrzykowska, Elzbieta Romelczyk-Baishya, Barbara Wojnarowicz, Jacek Sokolova, Marina Szlazak, Karol Swieszkowski, Wojciech Locs, Janis Lojkowski, Witold Nanomaterials (Basel) Article Composites made of a biodegradable polymer, e.g., polylactic acid (PLA) and hydroxyapatite nanoparticles (HAP NPs) are promising orthopedic materials. There is a particular need for biodegradable hybrid nanocomposites with strong mechanical properties. However, obtaining such composites is challenging, since nanoparticles tend to agglomerate, and it is difficult to achieve good bonding between the hydrophilic ceramic and the hydrophobic polymer. This paper describes a two-step technology for obtaining a ceramic matrix composite. The first step is the preparation of composite granules. The granules are obtained by infiltration of porous granules of HAP NPs with PLA through high-pressure infiltration. The homogeneous ceramic-polymer granules are 80 μm in diameter, and the composite granules are 80 wt% HAP NPs. The second step is consolidation of the granules using high pressure. This is performed in three variants: Uniaxial pressing with the pressure of up to 1000 MPa at room temperature, warm isostatic compaction (75 MPa at 155 °C), and a combination of the two methods. The combined methods result in the highest densification (99%) and strongest mechanical properties; the compressive strength is 374 MPa. The structure of the ceramic matrix composite is homogeneous. Good adhesion between the inorganic and the organic component is observable using scanning electron microscopy. MDPI 2020-05-30 /pmc/articles/PMC7352493/ /pubmed/32486301 http://dx.doi.org/10.3390/nano10061060 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pietrzykowska, Elzbieta
Romelczyk-Baishya, Barbara
Wojnarowicz, Jacek
Sokolova, Marina
Szlazak, Karol
Swieszkowski, Wojciech
Locs, Janis
Lojkowski, Witold
Preparation of a Ceramic Matrix Composite Made of Hydroxyapatite Nanoparticles and Polylactic Acid by Consolidation of Composite Granules
title Preparation of a Ceramic Matrix Composite Made of Hydroxyapatite Nanoparticles and Polylactic Acid by Consolidation of Composite Granules
title_full Preparation of a Ceramic Matrix Composite Made of Hydroxyapatite Nanoparticles and Polylactic Acid by Consolidation of Composite Granules
title_fullStr Preparation of a Ceramic Matrix Composite Made of Hydroxyapatite Nanoparticles and Polylactic Acid by Consolidation of Composite Granules
title_full_unstemmed Preparation of a Ceramic Matrix Composite Made of Hydroxyapatite Nanoparticles and Polylactic Acid by Consolidation of Composite Granules
title_short Preparation of a Ceramic Matrix Composite Made of Hydroxyapatite Nanoparticles and Polylactic Acid by Consolidation of Composite Granules
title_sort preparation of a ceramic matrix composite made of hydroxyapatite nanoparticles and polylactic acid by consolidation of composite granules
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352493/
https://www.ncbi.nlm.nih.gov/pubmed/32486301
http://dx.doi.org/10.3390/nano10061060
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