ABL Genomic Editing Sufficiently Abolishes Oncogenesis of Human Chronic Myeloid Leukemia Cells In Vitro and In Vivo

Chronic myelogenous leukemia (CML) is the most common type of leukemia in adults, and more than 90% of CML patients harbor the abnormal Philadelphia chromosome (Ph) that encodes the BCR-ABL oncoprotein. Although the ABL kinase inhibitor (imatinib) has proven to be very effective in achieving high re...

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Detalles Bibliográficos
Autores principales: Chen, Shu-Huey, Hsieh, Yao-Yu, Tzeng, Huey-En, Lin, Chun-Yu, Hsu, Kai-Wen, Chiang, Yun-Shan, Lin, Su-Mei, Su, Ming-Jang, Hsieh, Wen-Shyang, Lee, Chia-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352505/
https://www.ncbi.nlm.nih.gov/pubmed/32485885
http://dx.doi.org/10.3390/cancers12061399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352505/
https://www.ncbi.nlm.nih.gov/pubmed/32485885
http://dx.doi.org/10.3390/cancers12061399

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