SSADH Variants Increase Susceptibility of U87 Cells to Mitochondrial Pro-Oxidant Insult

Succinate semialdehyde dehydrogenase (SSADH) is a mitochondrial enzyme, encoded by ALDH5A1, mainly involved in γ-aminobutyric acid (GABA) catabolism and energy supply of neuronal cells, possibly contributing to antioxidant defense. This study aimed to further investigate the antioxidant role of SSAD...

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Detalles Bibliográficos
Autores principales: Menduti, Giovanna, Vitaliti, Alessandra, Capo, Concetta Rosa, Lettieri-Barbato, Daniele, Aquilano, Katia, Malaspina, Patrizia, Rossi, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352567/
https://www.ncbi.nlm.nih.gov/pubmed/32575506
http://dx.doi.org/10.3390/ijms21124374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352567/
https://www.ncbi.nlm.nih.gov/pubmed/32575506
http://dx.doi.org/10.3390/ijms21124374

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