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Acquisition of Cisplatin Resistance Shifts Head and Neck Squamous Cell Carcinoma Metabolism toward Neutralization of Oxidative Stress
Background: Cisplatin (CDDP) is commonly utilized in the treatment of advanced solid tumors including head and neck squamous cell carcinoma (HNSCC). Cisplatin response remains highly variable among individual tumors and development of cisplatin resistance is common. We hypothesized that development...
Autores principales: | Yu, Wangjie, Chen, Yunyun, Putluri, Nagireddy, Coarfa, Cristian, Robertson, Matthew J., Putluri, Vasanta, Stossi, Fabio, Dubrulle, Julien, Mancini, Michael A., Pang, Jonathan C., Nguyen, Trung, Baluya, Dodge, Myers, Jeffrey N., Lai, Stephen Y., Sandulache, Vlad C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352569/ https://www.ncbi.nlm.nih.gov/pubmed/32599707 http://dx.doi.org/10.3390/cancers12061670 |
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