DUBs Activating the Hedgehog Signaling Pathway: A Promising Therapeutic Target in Cancer

The Hedgehog (HH) pathway governs cell proliferation and patterning during embryonic development and is involved in regeneration, homeostasis and stem cell maintenance in adult tissues. The activity of this signaling is finely modulated at multiple levels and its dysregulation contributes to the ons...

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Detalles Bibliográficos
Autores principales: Bufalieri, Francesca, Lospinoso Severini, Ludovica, Caimano, Miriam, Infante, Paola, Di Marcotullio, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352588/
https://www.ncbi.nlm.nih.gov/pubmed/32531973
http://dx.doi.org/10.3390/cancers12061518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352588/
https://www.ncbi.nlm.nih.gov/pubmed/32531973
http://dx.doi.org/10.3390/cancers12061518

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