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Active RAC1 Promotes Tumorigenic Phenotypes and Therapy Resistance in Solid Tumors

Acting as molecular switches, all three members of the Guanosine triphosphate (GTP)-ase-family, Ras-related C3 botulinum toxin substrate (RAC), Rho, and Cdc42 contribute to various processes of oncogenic transformations in several solid tumors. We have reviewed the distribution of patterns regarding...

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Detalles Bibliográficos
Autores principales: De, Pradip, Rozeboom, Brett James, Aske, Jennifer Carlson, Dey, Nandini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352592/
https://www.ncbi.nlm.nih.gov/pubmed/32545340
http://dx.doi.org/10.3390/cancers12061541