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Active RAC1 Promotes Tumorigenic Phenotypes and Therapy Resistance in Solid Tumors
Acting as molecular switches, all three members of the Guanosine triphosphate (GTP)-ase-family, Ras-related C3 botulinum toxin substrate (RAC), Rho, and Cdc42 contribute to various processes of oncogenic transformations in several solid tumors. We have reviewed the distribution of patterns regarding...
Autores principales: | De, Pradip, Rozeboom, Brett James, Aske, Jennifer Carlson, Dey, Nandini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352592/ https://www.ncbi.nlm.nih.gov/pubmed/32545340 http://dx.doi.org/10.3390/cancers12061541 |
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