Diagnostic and Therapeutic Applications of Exosomes in Cancer with a Special Focus on Head and Neck Squamous Cell Carcinoma (HNSCC)

Exosomes are nanovesicles part of a recently described intercellular communication system. Their properties seem promising as a biomarker in cancer research, where more sensitive monitoring and therapeutic applications are desperately needed. In the case of head and neck squamous cell carcinoma (HNS...

Descripción completa

Detalles Bibliográficos
Autores principales: Ebnoether, Eliane, Muller, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352611/
https://www.ncbi.nlm.nih.gov/pubmed/32570802
http://dx.doi.org/10.3390/ijms21124344
_version_ 1783557678388215808
author Ebnoether, Eliane
Muller, Laurent
author_facet Ebnoether, Eliane
Muller, Laurent
author_sort Ebnoether, Eliane
collection PubMed
description Exosomes are nanovesicles part of a recently described intercellular communication system. Their properties seem promising as a biomarker in cancer research, where more sensitive monitoring and therapeutic applications are desperately needed. In the case of head and neck squamous cell carcinoma (HNSCC), overall survival often remains poor, although huge technological advancements in the treatment of this disease have been made. In the following review, diagnostic and therapeutic properties are highlighted and summarised. Impressive first results have been obtained but more research is needed to implement these innovative techniques into daily clinical routines.
format Online
Article
Text
id pubmed-7352611
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-73526112020-07-21 Diagnostic and Therapeutic Applications of Exosomes in Cancer with a Special Focus on Head and Neck Squamous Cell Carcinoma (HNSCC) Ebnoether, Eliane Muller, Laurent Int J Mol Sci Review Exosomes are nanovesicles part of a recently described intercellular communication system. Their properties seem promising as a biomarker in cancer research, where more sensitive monitoring and therapeutic applications are desperately needed. In the case of head and neck squamous cell carcinoma (HNSCC), overall survival often remains poor, although huge technological advancements in the treatment of this disease have been made. In the following review, diagnostic and therapeutic properties are highlighted and summarised. Impressive first results have been obtained but more research is needed to implement these innovative techniques into daily clinical routines. MDPI 2020-06-18 /pmc/articles/PMC7352611/ /pubmed/32570802 http://dx.doi.org/10.3390/ijms21124344 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ebnoether, Eliane
Muller, Laurent
Diagnostic and Therapeutic Applications of Exosomes in Cancer with a Special Focus on Head and Neck Squamous Cell Carcinoma (HNSCC)
title Diagnostic and Therapeutic Applications of Exosomes in Cancer with a Special Focus on Head and Neck Squamous Cell Carcinoma (HNSCC)
title_full Diagnostic and Therapeutic Applications of Exosomes in Cancer with a Special Focus on Head and Neck Squamous Cell Carcinoma (HNSCC)
title_fullStr Diagnostic and Therapeutic Applications of Exosomes in Cancer with a Special Focus on Head and Neck Squamous Cell Carcinoma (HNSCC)
title_full_unstemmed Diagnostic and Therapeutic Applications of Exosomes in Cancer with a Special Focus on Head and Neck Squamous Cell Carcinoma (HNSCC)
title_short Diagnostic and Therapeutic Applications of Exosomes in Cancer with a Special Focus on Head and Neck Squamous Cell Carcinoma (HNSCC)
title_sort diagnostic and therapeutic applications of exosomes in cancer with a special focus on head and neck squamous cell carcinoma (hnscc)
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352611/
https://www.ncbi.nlm.nih.gov/pubmed/32570802
http://dx.doi.org/10.3390/ijms21124344
work_keys_str_mv AT ebnoethereliane diagnosticandtherapeuticapplicationsofexosomesincancerwithaspecialfocusonheadandnecksquamouscellcarcinomahnscc
AT mullerlaurent diagnosticandtherapeuticapplicationsofexosomesincancerwithaspecialfocusonheadandnecksquamouscellcarcinomahnscc

Ejemplares similares