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Sorafenib Resistance in Hepatocellular Carcinoma: The Relevance of Genetic Heterogeneity
Despite advances in biomedicine, the incidence and the mortality of hepatocellular carcinoma (HCC) remain high. The majority of HCC cases are diagnosed in later stages leading to the less than optimal outcome of the treatments. Molecular targeted therapy with sorafenib, a dual-target inhibitor targe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352671/ https://www.ncbi.nlm.nih.gov/pubmed/32549224 http://dx.doi.org/10.3390/cancers12061576 |