Cargando…

The Value of Laboratory Parameters for Anemia, Renal Function, Systemic Inflammation and Nutritional Status as Predictors for Outcome in Elderly Patients with Head-and-Neck Cancers

The purpose of this study was to evaluate the value of routine blood markers regarding their predictive potential for treatment outcomes of elderly head-and-neck squamous cell carcinoma (HNSCC) patients. In total, 246 elderly HNSCC patients (≥65 years) undergoing (chemo)radiotherapy from 2010 to 201...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rühle, Alexander, Haehl, Erik, David, Hélène, Kalckreuth, Tobias, Sprave, Tanja, Stoian, Raluca, Zamboglou, Constantinos, Gkika, Eleni, Knopf, Andreas, Grosu, Anca-Ligia, Nicolay, Nils Henrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352755/ https://www.ncbi.nlm.nih.gov/pubmed/32604773 http://dx.doi.org/10.3390/cancers12061698

Ejemplares similares

Surviving Elderly Patients with Head-and-Neck Squamous Cell Carcinoma—What Is the Long-Term Quality of Life after Curative Radiotherapy?
por: Rühle, Alexander, et al.
Publicado: (2021)

Radiation-induced toxicities and outcomes after radiotherapy are independent of patient age in elderly salivary gland cancer patients: results from a matched-pair analysis of a rare disease
por: Rühle, Alexander, et al.
Publicado: (2020)

The value of moderate dose escalation for re-irradiation of recurrent or second primary head-and-neck cancer
por: Rühle, Alexander, et al.
Publicado: (2020)

The value of primary and adjuvant radiotherapy for cutaneous squamous cell carcinomas of the head-and-neck region in the elderly
por: Haehl, Erik, et al.
Publicado: (2021)

Radiotherapy for geriatric head-and-neck cancer patients: what is the value of standard treatment in the elderly?
por: Haehl, Erik, et al.
Publicado: (2020)

Patterns-of-Care Analysis for Radiotherapy of Elderly Head-and-Neck Cancer Patients: A Trinational Survey in Germany, Austria and Switzerland
por: Haehl, Erik, et al.
Publicado: (2022)

App-Controlled Treatment Monitoring and Support for Head and Neck Cancer Patients (APCOT): Protocol for a Prospective Randomized Controlled Trial
por: Sprave, Tanja, et al.
Publicado: (2020)

Radiotherapeutic management of cervical lymph node metastases from an unknown primary site – experiences from a large cohort treated with modern radiation techniques
por: Sprave, Tanja, et al.
Publicado: (2020)

Palliative radiotherapy of bone metastases in octogenarians: How do the oldest olds respond? Results from a tertiary cancer center with 288 treated patients
por: Rühle, Alexander, et al.
Publicado: (2022)

Radiotherapy for nonagenarians: the value of biological versus chronological age
por: Sprave, Tanja, et al.
Publicado: (2020)

Prognostic value of tumor-infiltrating immune cells and immune checkpoints in elderly head-and-neck squamous cell carcinoma patients undergoing definitive (chemo)radiotherapy
por: Rühle, Alexander, et al.
Publicado: (2022)

Patient reported outcomes based on EQ-5D-5L questionnaires in head and neck cancer patients: a real-world study
por: Sprave, Tanja, et al.
Publicado: (2022)

App-Controlled Treatment Monitoring and Support for Patients With Head and Neck Cancer Undergoing Radiotherapy: Results From a Prospective Randomized Controlled Trial
por: Sprave, Tanja, et al.
Publicado: (2023)

Intraoperative radiotherapy boost as part of breast-conservation therapy for breast cancer: a single-institution retrospective analysis
por: Stoian, Raluca, et al.
Publicado: (2021)

Risk Factors for Biochemical Recurrence After PSMA-PET-Guided Definitive Radiotherapy in Patients With De Novo Lymph Node-Positive Prostate Cancer
por: Spohn, Simon K.B., et al.
Publicado: (2022)

Low-dose radiotherapy for painful osteoarthritis of the elderly: A multicenter analysis of 970 patients with 1185 treated sites
por: Rühle, Alexander, et al.
Publicado: (2021)

Cost effectiveness and health-related quality of life of chemoradiotherapy versus radiation therapy alone in elderly head and neck cancer patients
por: Sprave, Tanja, et al.
Publicado: (2022)

Sarcopenia as a Prognostic Marker in Elderly Head and Neck Squamous Cell Carcinoma Patients Undergoing (Chemo-)Radiation
por: Haehl, Erik, et al.
Publicado: (2022)

The influence of antibiotic administration on the outcomes of head-and-neck squamous cell carcinoma patients undergoing definitive (chemo)radiation
por: Rühle, Alexander, et al.
Publicado: (2023)

Changes in Blood Biomarkers of Angiogenesis and Immune Modulation after Radiation Therapy and Their Association with Outcomes in Thoracic Malignancies
por: Gkika, Eleni, et al.
Publicado: (2021)

De-Escalation Strategies of (Chemo)Radiation for Head-and-Neck Squamous Cell Cancers—HPV and Beyond
por: Rühle, Alexander, et al.
Publicado: (2021)

Intraindividual comparison between (68)Ga-PSMA-PET/CT and mpMRI for intraprostatic tumor delineation in patients with primary prostate cancer: a retrospective analysis in 101 patients
por: Spohn, Simon, et al.
Publicado: (2020)

Deep inspiration breath-hold radiation therapy in left-sided breast cancer patients: a single-institution retrospective dosimetric analysis of organs at risk doses
por: Wolf, Jule, et al.
Publicado: (2022)

The value of plasma hypoxia markers for predicting imaging-based hypoxia in patients with head-and-neck cancers undergoing definitive chemoradiation
por: Rühle, Alexander, et al.
Publicado: (2022)

(18)F-FMISO-PET Hypoxia Monitoring for Head-and-Neck Cancer Patients: Radiomics Analyses Predict the Outcome of Chemo-Radiotherapy
por: Carles, Montserrat, et al.
Publicado: (2021)

The Particle Radiobiology of Multipotent Mesenchymal Stromal Cells: A Key to Mitigating Radiation-Induced Tissue Toxicities in Cancer Treatment and Beyond?
por: Rühle, Alexander, et al.
Publicado: (2021)

Comparison of intraoperative radiotherapy as a boost vs. simultaneously integrated boosts after breast-conserving therapy for breast cancer
por: Stoian, Raluca, et al.
Publicado: (2023)

The Role of Palliative Radiotherapy in the Treatment of Spinal Bone Metastases from Head and Neck Tumors—A Multicenter Analysis of a Rare Event
por: Bostel, Tilman, et al.
Publicado: (2020)

Interleukin-6 as surrogate marker for imaging-based hypoxia dynamics in patients with head-and-neck cancers undergoing definitive chemoradiation—results from a prospective pilot trial
por: Rühle, Alexander, et al.
Publicado: (2021)

Hypoxia dynamics on FMISO-PET in combination with PD-1/PD-L1 expression has an impact on the clinical outcome of patients with Head-and-neck Squamous Cell Carcinoma undergoing Chemoradiation
por: Rühle, Alexander, et al.
Publicado: (2020)

Incidental irradiation of the regional lymph nodes during deep inspiration breath-hold radiation therapy in left-sided breast cancer patients: a dosimetric analysis
por: Wolf, Jule, et al.
Publicado: (2022)

FDG-PET Radiomics for Response Monitoring in Non-Small-Cell Lung Cancer Treated with Radiation Therapy
por: Carles, Montserrat, et al.
Publicado: (2021)

Human Mesenchymal Stromal Cells Do Not Cause Radioprotection of Head-and-Neck Squamous Cell Carcinoma
por: Rühle, Alexander, et al.
Publicado: (2022)

Influence of Urethra Sparing on Tumor Control Probability and Normal Tissue Complication Probability in Focal Dose Escalated Hypofractionated Radiotherapy: A Planning Study Based on Histopathology Reference
por: Spohn, Simon K. B., et al.
Publicado: (2021)

Evaluation of Concomitant Systemic Treatment in Older Adults With Head and Neck Squamous Cell Carcinoma Undergoing Definitive Radiotherapy
por: Rühle, Alexander, et al.
Publicado: (2023)

Comparative Analyses of Two Established Scores to Assess the Stability of Spinal Bone Metastases Before and After Palliative Radiotherapy
por: Bostel, Tilman, et al.
Publicado: (2021)

Intraindividual Comparison Between [(18)F] PSMA-1007 PET/CT and Multiparametric MRI for Radiotherapy Planning in Primary Prostate Cancer Patients
por: Marinescu, Ioana M., et al.
Publicado: (2022)

Comparison of Manual and Semi-Automatic [(18)F]PSMA-1007 PET Based Contouring Techniques for Intraprostatic Tumor Delineation in Patients With Primary Prostate Cancer and Validation With Histopathology as Standard of Reference
por: Spohn, Simon K. B., et al.
Publicado: (2020)

The Evolving Role of Radiation Therapy in the Treatment of Biliary Tract Cancer
por: Gkika, Eleni, et al.
Publicado: (2020)

The impact of the co-registration technique and analysis methodology in comparison studies between advanced imaging modalities and whole-mount-histology reference in primary prostate cancer
por: Zamboglou, Constantinos, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lt9vo1rdhjf07ibooge6ucbbc7