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The Role of Alternative RNA Splicing in the Regulation of hTERT, Telomerase, and Telomeres: Implications for Cancer Therapeutics

Alternative RNA splicing impacts the majority (>90%) of eukaryotic multi-exon genes, expanding the coding capacity and regulating the abundance of gene isoforms. Telomerase (hTERT) is a key example of a gene that is alternatively spliced during human fetal development and becomes dysregulated in...

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Detalles Bibliográficos
Autores principales:	Slusher, Aaron L., Kim, Jeongjin JJ, Ludlow, Andrew T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352778/ https://www.ncbi.nlm.nih.gov/pubmed/32531916 http://dx.doi.org/10.3390/cancers12061514

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